The term "citrulline" comes from the Latin name for watermelon - citrullus, as this substance was first isolated from its rind. It is an alpha-keto acid, which is needed for the synthesis of arginine and other substances necessary for our body, to neutralize and remove the decomposition products of amino acids. Citrulline molecules are basic in the structure of the nerve sheath, hair and nails.
Nutritional athletes are well aware of citrulline's ability to improve fitness and performance. In the past few decades, and especially now, during the Covid-19 pandemic, people who are not involved in sports or fitness have also become familiar with the beneficial effects of citrulline.
The benefits of citrulline for the body
Citrulline is a natural precursor to arginine. This is why citrulline supplements are sometimes better than arginine supplements. Its molecules are more bioavailable, prevent the first pass metabolism through the liver, have a longer circulation time in the blood.
Citrulline is used in medicine as an adjuvant therapy:
with chronic diseases of the cardiovascular system, liver, kidneys, diabetes mellitus, chronic fatigue syndrome, professional burnout;
to protect the inner epithelial layer of blood vessels, their vasodilation and regulation of blood pressure;
for myo- and neuroprotection.
It is also worth noting that the properties and effects of citrulline, including reducing inflammation and activating immunity, allow it to be used in the early and late stages of treatment, as well as for the rehabilitation of anemic conditions after acute respiratory infections and acute respiratory viral infections, which include Covid-19.